Antimutagenicity and Anticarcinogenicity of Terpenoids
نویسندگان
چکیده
منابع مشابه
Inhibition of Carcinogen-Activating Cytochrome P450 Enzymes by Xenobiotic Chemicals in Relation to Antimutagenicity and Anticarcinogenicity
A variety of xenobiotic chemicals, such as polycyclic aromatic hydrocarbons (PAHs), aryl- and heterocyclic amines and tobacco related nitrosamines, are ubiquitous environmental carcinogens and are required to be activated to chemically reactive metabolites by xenobiotic-metabolizing enzymes, including cytochrome P450 (P450 or CYP), in order to initiate cell transformation. Of various human P450...
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Naturally occurring anti-mutagenic principles present in plants, human diet and other sources have protective effects against mutagens. Anthraquinones (AQs) considered one of the major plant phenolic pigments that contain many members, have evidenced the capability for inhibiting the mutagenicity toward Salmonella typhimurium of a number of mutagens. Not only genotoxicity/carcinogenesis is caus...
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Terpenoids (synonymous with isoprenoids or isopentenoids) are a diverse class of natural products that are derived biosynthetically from an intermediate with a simple five-carbon skeleton (isopentane); higher terpenoids are complex structures that possess minimally between 20 and 40 carbon atoms. Higher terpenoids evolved coincidentally with the evolution of life and play multiple functions in ...
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Antimutagenicity of the water extracts prepared from the storage roots of four varieties of sweetpotato with different flesh colors was investigated using Salmonella typhimurium TA 98. The extract from the whole roots of the purple-colored Ayamurasaki variety effectively decreased the reverse mutation induced not only by Trp-P-1, Trp-P-2, IQ, B[a]P, and 4-NQO but also by dimethyl sulfoxide extr...
متن کاملAntimutagenicity of ethanol extract of Derris brevipes
Derris brevipes, a common medicinal plant, has multiple uses in traditional system of medicine and in particular it is used as a memory-enhancing agent for centuries. The plant and its extracts have been evaluated for number of activities like anti-inflammatory, cardio-tonic, sedative and neuron-muscular. The plant extract was evaluated for Antimutagenicity and mutagenicity studies in order to ...
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ژورنال
عنوان ژورنال: Journal of Japan Oil Chemists' Society
سال: 1999
ISSN: 1341-8327,1884-1996
DOI: 10.5650/jos1996.48.1057